5,560 research outputs found

    Walking across Wikipedia: a scale-free network model of semantic memory retrieval.

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    Semantic knowledge has been investigated using both online and offline methods. One common online method is category recall, in which members of a semantic category like "animals" are retrieved in a given period of time. The order, timing, and number of retrievals are used as assays of semantic memory processes. One common offline method is corpus analysis, in which the structure of semantic knowledge is extracted from texts using co-occurrence or encyclopedic methods. Online measures of semantic processing, as well as offline measures of semantic structure, have yielded data resembling inverse power law distributions. The aim of the present study is to investigate whether these patterns in data might be related. A semantic network model of animal knowledge is formulated on the basis of Wikipedia pages and their overlap in word probability distributions. The network is scale-free, in that node degree is related to node frequency as an inverse power law. A random walk over this network is shown to simulate a number of results from a category recall experiment, including power law-like distributions of inter-response intervals. Results are discussed in terms of theories of semantic structure and processing

    Cold tolerance of the eastern subterranean termite, Reticulitermes flavipes (Isoptera: Rhinotermitidae), in Ontario.

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    We characterized the cold tolerance of natural populations of the Eastern subterranean termite (Reticulitermes flavipes (Kollar) [Isoptera, Rhinotermitidae]) in southwestern Ontario, Canada. We measured cold tolerance in workers from six colonies of termites established from Pelee Island in Lake Erie, and Point Pelee National Park. The mean critical thermal minimum, at which termites entered chill coma, ranged from 8.1 to 5.7°C. Mean supercooling points (SCP, the temperature at which individuals freeze) ranged from -4 to -4.6°C, and did not differ significantly between colonies, nor was SCP dependent on body size. Individuals survived brief exposure to low temperatures, as long as they did not freeze, but internal ice formation was always lethal, suggesting a freeze avoiding strategy. The LT50 (temperature at which 50% of individuals were killed by a 1 h exposure) was -5.1°C, but all individuals could survive -2°C for at least 72 h. Low temperature acclimation (12°C, 7 d) or hardening (4°C, 2 h) had no impact on the SCP, but acclimation did slightly increase the critical thermal minimum, making the termites less cold tolerant. We conclude that R. flavipes is not particularly cold tolerant, and likely relies on burrowing deep into the soil to avoid exposure to temperature to extremes

    The ARIN Virtual Reality Experience and Writing about VR for a Popular Audience

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    ARIN is a virtual reality, sci-fi horror experience for the HTC Vive, which incorporates visual and tactile performance elements and staging to increase the viewer’s sense of immersion. The first part of this paper covers the design process of the ARIN Virtual Reality Experience from concept to completion including playtesting and critical analysis. The second, written individually by Izzie Schiavone, explores how popular science writing uses the Hero\u27s Journey as a narrative structure that facilitates the explanation of scientific knowledge for a popular audience. The findings from studying popular science writing were used to write an article about VR and the development of the ARIN Virtual Reality Experience

    Operational reliability assessment of the GEOS A spacecraft

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    Decision theory application to GEOS A spacecraft operational reliability assessmen

    Engineering molecularly-active nanoplasmonic surfaces for DNA detection via colorimetry and Raman scattering

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    We report a novel nanophotonic biosensor surface capable of both colorimetric detection and Raman-scattered detection of DNA infection markers at extreme sensitivities. Combining direct-write lithography, dip-pen nanolithography based DNA patterning, and molecular self-assembly, we create molecularly-active plasmonic nanostructures onto which metallic nanoparticles are located via DNA-hybridization. Arraying these structures enables optical surfaces that change state when contacted by specific DNA sequences; shifting the surface color while simultaneously generating strong Raman-scattering signals. Patterning the DNA markers onto the plasmonic surface as micro-scale symbols results in easily identifiable color shifts, making this technique applicable to multiplexed lab-on-a-chip and point-of-care diagnostic applications

    Increased axonal bouton dynamics in the aging mouse cortex

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    Aging is a major risk factor for many neurological diseases and is associated with mild cognitive decline. Previous studies suggest that aging is accompanied by reduced synapse number and synaptic plasticity in specific brain regions. However, most studies, to date, used either postmortem or ex vivo preparations and lacked key in vivo evidence. Thus, whether neuronal arbors and synaptic structures remain dynamic in the intact aged brain and whether specific synaptic deficits arise during aging remains unknown. Here we used in vivo two-photon imaging and a unique analysis method to rigorously measure and track the size and location of axonal boutons in aged mice. Unexpectedly, the aged cortex shows circuit-specific increased rates of axonal bouton formation, elimination, and destabilization. Compared with the young adult brain, large (i.e., strong) boutons show 10-fold higher rates of destabilization and 20-fold higher turnover in the aged cortex. Size fluctuations of persistent boutons, believed to encode long-term memories, also are larger in the aged brain, whereas bouton size and density are not affected. Our data uncover a striking and unexpected increase in axonal bouton dynamics in the aged cortex. The increased turnover and destabilization rates of large boutons indicate that learning and memory deficits in the aged brain arise not through an inability to form new synapses but rather through decreased synaptic tenacity. Overall our study suggests that increased synaptic structural dynamics in specific cortical circuits may be a mechanism for age-related cognitive decline

    SERS enhancement of silver nanoparticles prepared by a template-directed triazole ligand strategy

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    Two advances in the development of a one-pot method to prepare silver nanoparticles (AgNPs) using the Tollens’ reagent are described. First, a template-directed process of AgNP synthesis using resorcinol triazole ligands bearing two pendent galactose sugars is shown. Second, the conversion of these AgNPs into SERS nanotags is demonstrated using malachite green isothiocyanate as the Raman reporter molecule

    SERS enhancement of silver nanoparticles prepared by a template-directed triazole ligand strategy

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    Two advances in the development of a one-pot method to prepare silver nanoparticles (AgNPs) using the Tollens' reagent are described. First, a template-directed process of AgNP synthesis using resorcinol triazole ligands bearing two pendent galactose sugars is shown. Second, the conversion of these AgNPs into SERS nanotags is demonstrated using malachite green isothiocyanate as the Raman reporter molecule

    Great Canadian LagerstÀtten 3. Late Ordovician Konservat-LagerstÀtten in Manitoba

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    Konservat-LagerstĂ€tten, deposits in which soft-bodied or lightly sclerotized fossils are preserved, are very rare in Ordovician strata. Three significant sites are known from Upper Ordovician rocks in Manitoba: at Cat Head – McBeth Point, William Lake, and Airport Cove. These sites are in two distinct sedimentary basins: the former two are in the Williston Basin, while the latter is in the Hudson Bay Basin. All three sites contain marine fossils, but each has a different assemblage that contributes a distinct piece of the diversity picture. Important groups represented at one or more of the sites include seaweeds (algae), sponges, cnidarian medusae (jellyfish), conulariids, trilobites, eurypterids, xiphosurids (horseshoe crabs), and pycnogonids (‘sea spiders’). The different biotas reflect depositional conditions at each site. Many of the fossils are unknown elsewhere in the Ordovician at the family level or higher. The province of Manitoba therefore makes a significant contribution to knowledge of Late Ordovician biodiversity.SOMMAIRELes lagerstĂ€tten de conservation, ces sĂ©diments contenant des fossiles d’organismes Ă  corps mou ou lĂ©gĂšrement sclĂ©rotisĂ©s particuliĂšrement bien conservĂ©s, sont trĂšs rares dans les strates ordoviciennes.  Trois sites d’importance sont connus dans des roches de l'Ordovicien supĂ©rieur Ă  Cat Head, Manitoba, soit McBeth Point, William Lake et  Airport Cove.  Ces sites sont situĂ©s dans deux bassins sĂ©dimentaires distincts : les deux premiers sont situĂ©s dans le bassin de Williston, tandis que le second est situĂ© dans le bassin de la baie d'Hudson.  Les trois sites contiennent des fossiles marins, mais chacun prĂ©sente un assemblage diffĂ©rent, chacun montrant une composante distincte de la diversitĂ© biologique d’alors.  Les groupes les plus importants reprĂ©sentĂ©s, dans un ou plusieurs de ces sites, sont les algues, les Ă©ponges, les cnidarian medusae (mĂ©duses), les conularides, les trilobites, les euryptĂ©rides, xiphosurides (limules) et pycnogonides.  Les diffĂ©rents biotopes reflĂštent les conditions de dĂ©pĂŽt de chaque site.  Nombre de ces fossiles sont inconnus ailleurs dans l'Ordovicien, au niveau de la famille ou du taxon supĂ©rieur de la classification.  Ainsi, la province du Manitoba offre-t-elle une contribution importante Ă  la connaissance de la biodiversitĂ© de l'Ordovicien supĂ©rieur
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